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Submitted
August 1, 2018
Accepted
December 10, 2020
Published
December 30, 2020
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Abstract

Objectives: To evaluate the spatial distribution of the epileptiform activity in electrical status epilepticus in sleep (ESES) and to correlate data from electroencephalograms (EEGs) with clinical and neuroimaging variables.


Methods: From 2008 to 2015, 162 reports (1.01%) out of 16,000 EEGs, from 23 patients, showed ESES. We selected one representative EEG per patient. Clinical data was collected retrospectively. Neuroimaging examinations were reviewed. The EEGs were classified as generalized ESES (ESESg) and focal ESES (ESESf) according to the distribution of epileptiform discharges.


Results: From the 23 patients, 5 were classified as ESESg and 18 as ESESf. In ESESf, there was a prevalence of focal epileptic discharges in the centrotemporal regions. Abnormal neuroimaging occurred in 100% of the patients with ESESg and in 38.9% of the patients with ESESf (p=0.037). Other clinical data did not show significant differences between the groups. All patients with ESESg had structural etiology, while only 39% of patients with ESESf had structural etiology and the remaining 61% potentially genetic epilepsies of the rolandic spectrum.


Conclusion: ESESg occurred predominantly in patients with structural lesions, while most patients with ESESf had normal neuroimaging scans and electrical dysfunction mainly in the rolandic region.


Significance: ESESg seems to occur mostly in structural epilepsies. Distinctly, ESESf occurs in epileptic syndromes within the functional spectrum of rolandic epilepsy.

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Copyright (c) 2021 Raphael R. Almeida, Ana Carolina Coan, Marilisa M Guerreiro

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Author Biography

Marilisa M Guerreiro, State University of Campinas (Unicamp)

Head, Department of Neurology

Chair, Child Neurology Unit

How to Cite
Almeida, R. R. ., Coan, A. C., & Guerreiro, M. M. (2020). Electrical Status Epilepticus in Sleep: Is this a Focal or Generalized Pattern?. Journal of the International Child Neurology Association, 1(1). https://doi.org/10.17724/jicna.2020.152
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