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Abstract
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder predominantly affecting the peripheral nervous system (PNS), characterised by muscle weakness and sensory disruption which may involve all four limbs[1]. CIDP affecting children is uncommon, with a large scale review in 2013 noting 143 documented cases described in the literature [2]. Central nervous system involvement has previously been described; however, optic neuropathy is an extremely rare manifestation of CIDP, with only a small number of cases previously reported (both unilateral and bilateral) in adult patients[3-5]. This report details a child who developed optic neuropathy in association with CIDP.
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Copyright (c) 2018 Nigel Colin Griffith
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References
- Mathey Emily K, Park Susanna B, Hughes Richard A C, Pollard John D, Armati Patricia J, Barnett Michael H, Taylor Bruce V, Dyck P James B, Kiernan Matthew C, Lin Cindy S-Y. Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype.. Journal of neurology, neurosurgery, and psychiatry.. 2015; 86(9)
- McMillan Hugh J, Kang Peter B, Jones H Royden, Darras Basil. Childhood chronic inflammatory demyelinating polyradiculoneuropathy: combined analysis of a large cohort and eleven published series.. Neuromuscular disorders : NMD.. 2013; 23(2)
- Holtkamp M, Zschenderlein R, Bruck W, Weber JR. Childhood chronic inflammatory demyelinating polyradiculoneuropathy: combined analysis of a large cohort and eleven published series.. Acta neuropathologica. 2001; 101(5)
- Lin K Y, Wang I H, Jou J R, Chu H J, Wei W, Lee S H, Lin S Y. Optic neuropathy in a patient with chronic inflammatory demyelinating polyneuropathy.. Eye (London, England). 2000; 14(6)
- Tsai D C, Lin P K, Lin K P, Kao K P, Liu J H. Bilateral optic neuritis related to chronic inflammatory demyelinating polyneuropathy.. Taiwan journal of ophthalmology. 2015; 5(1)
- Holder GE. Electrophysiological assessment of optic nerve disease.. Eye. 2004; 18(11):1133-43.
- Desai J, Ramos-Platt L, Mitchell WG. Treatment of pediatric chronic inflammatory demyelinating polyneuropathy: Challenges, controversies and questions.. Annals of Indian Academy of Neurology.. 2015; 18(3):327-30.
References
Mathey Emily K, Park Susanna B, Hughes Richard A C, Pollard John D, Armati Patricia J, Barnett Michael H, Taylor Bruce V, Dyck P James B, Kiernan Matthew C, Lin Cindy S-Y. Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype.. Journal of neurology, neurosurgery, and psychiatry.. 2015; 86(9)
McMillan Hugh J, Kang Peter B, Jones H Royden, Darras Basil. Childhood chronic inflammatory demyelinating polyradiculoneuropathy: combined analysis of a large cohort and eleven published series.. Neuromuscular disorders : NMD.. 2013; 23(2)
Holtkamp M, Zschenderlein R, Bruck W, Weber JR. Childhood chronic inflammatory demyelinating polyradiculoneuropathy: combined analysis of a large cohort and eleven published series.. Acta neuropathologica. 2001; 101(5)
Lin K Y, Wang I H, Jou J R, Chu H J, Wei W, Lee S H, Lin S Y. Optic neuropathy in a patient with chronic inflammatory demyelinating polyneuropathy.. Eye (London, England). 2000; 14(6)
Tsai D C, Lin P K, Lin K P, Kao K P, Liu J H. Bilateral optic neuritis related to chronic inflammatory demyelinating polyneuropathy.. Taiwan journal of ophthalmology. 2015; 5(1)
Holder GE. Electrophysiological assessment of optic nerve disease.. Eye. 2004; 18(11):1133-43.
Desai J, Ramos-Platt L, Mitchell WG. Treatment of pediatric chronic inflammatory demyelinating polyneuropathy: Challenges, controversies and questions.. Annals of Indian Academy of Neurology.. 2015; 18(3):327-30.